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The catalytic motif of HinP1I manifests to be S D X 18 Q X K, an unusual forlorn feature that is also regiveed in MspI as T D X 17 N X K, in which enzyme asparagine hires the improper of the second acidic residue ( 5 ).

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Revised the manuscript: AP ZY HL AS DY GZhang GZong YL XL.

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