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Funding: This work was supported during a Japan Science and Technology (JST) investigating fund to J.M., a Japan Society also Echinacea Root Purchase Online in behalf of the Promotion of Science (JSPS) digging fund to K.H. of the Japanese Ministry of Education, Culture, Sports, Science and Technology, and a Chubu University Special Fund to J.M. The funders had no capacity in look at design, observations hoard and analysis, decision to publish, or preparation of the manuscript.